Hu's Lab(Signal Transduction and Targeted Gene Therapy)

 

Hu's Homepage

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Current Members. in Dr. Hu's Lab

Xinxu Yuan, PhD

  • 2024-present, Senior Scientist, Department of Anatomy and Neurobiology, VCU
  • 2022-2024, Research Scientist, Department of Pharmacology and Toxicology, VCU
  • 2014-2022 Postdoctoral Fellow, Department of Pharmacology and Toxicology, VCU
  • 2011-2013 Postdoctoral Associate, Medical University of South Carolina
  • 2009-2011 Lab Manager, Beijing Genomic Institute, P. R. China
  • 2004-2009 Ph.D., Chinese Academy of Agricultural Sciences
  • 2000-2004 BS, Henan Agricultural University, P. R. China

Current Research Focus: 1. Identification of novel BBB-crossing and microglia-targeting AAV-BM for CRISPR/Cas delivery to cure NeuroHIV and other neurodegenerative diseases. 2. Optimize multiplexed supercompact Cas12f editors for HIV eradication.

 

Dabbu Kumar Jaijyan, PhD

  • 2024-present      Assistant Professor, Virginia Commonwealth University, Richmond, VA.
  • 2023-2023           Adjunct Assistant Professor, The College of New Jersey (TCNJ)
  • 2019-2023           Research Scientist, Rutgers University, New Jersey, USA
  • 2016-2023           Teaching assistant and lecturer, Rutgers University, New Jersey, USA
  • 2014-2019           Postdoctoral research fellow, Rutgers University, New Jersey, USA
  • 2014-2019           PhD, National Institute of Immunology, India
  • 2012-2014           Senior research fellow, National Institute of Immunology, India
  • 2008-2012           Junior research fellow, National Institute of Immunology, India
  • 2003-2008           BS, Kirorimal College, Delhi University, India

 

Current Research Focus: 1. Explore targeted virus-like particle (endogenous retrovirus and AAV) delivery of CRISPR/Cas editor for infectious diseases, autoimmunity and aging; 2. Develop BBB-crossing lentivirus-like particles for gene therapy in CNS injuries and diseases; 3. Devlope novel live-attenuated and replication-defected vaccine against DNA viruses

Abdul Rasheed Baloch, PhD

  • 2023 (July -)      Post-Doctoral Fellow   Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University, Richmond, USA
  • 2023 (Feb to June)        Post-Doctoral Fellow   Temple University Lewis Katz School of Medicine, Philadelphia, USA
  • 2022     Research Officer          Dr Panjwani Center for Molecular Medicine and Drug Research (PCMD), International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Pakistan
  • 2021     Research Scientist        Czech Academy of Sciences (CAS), Prague, Czech Republic
  • 2019     PhD (Development Biology/Zootechnics)        University of South Bohemia in Ceske Budejovice, Czech Republic
  • 2014     MSc (Basic Veterinary Medicine)        Northwest A&F University, China
  • 2011     DVM (Doctor of Veterinary Medicine)            Sindh Agriculture University, Tandojam, Pakistan
  • 2005     FSc      Board of Intermediate & Secondary Education (BISE) Hyderabad, Pakistan

Current Research Focus: 1. T cell-targeted lipid nanoparticle (LNP) and lentivirus-like particles (LVLP) delivery of CRISPR/Cas editor for HIV cure; 2. Virus infection in human iPSC-derived vascularized microglia-containing cerebral organoids (vMCO); 3. CRIPSR/Cas-mediated manipulation of inflammasome signaling in human iPSC and vMCO.

Abdul Sattar Baloch, DVM, PhD

  • 2024-present     Postdoc Associate, Department of Anatomy and Neurobiology, VCU
  • 2017-2023         PhD, Nanjing Agricultural University, Jiangsu, China.
  • 2014-2017        Research Assistant, Sindh Central Veterinary Diagnostic Laboratory (CVDL) Tando Jam Sindh, Pakistan
  • 2012 – 2014      M.Phil, Sindh Agriculture University Tando jam Sindh, Pakistan.
  • 2006 – 2011      DVM (Doctor of Veterinary Medicine), Sindh Agriculture University Tando jam Sindh, Pakistan
  • 2003 – 2005      Intermediate (Pre-Medical), Board of Intermediate & Secondary Education (BISE), Hyderabad, Sindh, Pakistan
  • 2001 – 2003      Matriculation (General Science), Board of Intermediate & Secondary Education (BISE), Hyderabad, Sindh, Pakistan

Current Research Focus: 1. Molecular mechanism of Exin21 boosting on antibody/vaccine/virus/recombinant protein production; 2. mRNA-based gene therapy.

Danmeng Zhang, MD, PhD

  • 2024- present   Postdoc Associate, Department of Anatomy and Neurobiology, VCU
  • 2018.4-2023.3 PhD, Psychiatry, Graduate School of Medicine, Kobe University, Japan
  • 2021-2022        Research Assistant, Department of Psychiatry, Graduate School of Medicine, Kobe University, Japan
  • 2018-2020        Teaching Assistant, Department of Psychiatry, Graduate School of Medicine, Kobe University, Japan
  • 2017.9-2018.3 Research student, Psychiatry, Graduate School of Medicine, Kobe University, Japan
  • 2015-2016        Internship, Qingdao Municipal Hospital, China
  • 2014-2015        Internship, First Affiliated Hospital of Dalian Medical University, China
  • 2011.9-2016.7 MD, Clinical Medicine, Dalian Medical University, China

Current Research Focus: 1. Role and mechanims of NIBP/TRAPPC9 signaling in neurodevelopmental disorders; 2. BBB-crossing and microglia-targeting AAV-BM screening; 3. CRIPSR/Cas-mediated human iPSC-derivded organoid modeling for genetic diseases;

FLFang Li, Lab Manager (2008-present)

 

Previous members

Postdoc and Visiting Scholar

Jianjun Liu, Ph.D, Postoc (2008-2009), -(Currently Associate Professor, The Third Military Medical University, Chonqing, China)

Leiting Yang, M.D., Ph.D. Visiting Scholar (2009-2010), -(Professor of Neurosurgery, Guangxi Medical University, Nanling, China)

Shu Liu, M.D. Visiting Scholar (2009-2010),-(Assoiate Professor, China Medical University, Shenyang, China)

Hong Wang, Ph.D. Visiting Scholar (2011-2013),-(Professor, ZheJiang provincial hospital, the First Hospital affiliated to Zhejiang University of Traditional Chinese Medicine)

Yonggang Zhang, Postdoc (2010-2015) and Research Associate (2015-2016), [Professor, Center for Stem Cell Research and Application, Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Chengdu 610052, China]

Chaoran Yin, Postdoc (2015-2017), -(Postdoc, Fox Chase Cancer Center, Temple University)

Ting Zhang, Postdoc (2015-2017)- Postdoc(2018-2022, Fox Chase Cancer Center, Temple University; Professor, Sichuan University)

Xiao Xiao, MD, MS, Visiting Research Scholar(2016-2018)

Mingyang Xin, MD, Visiting Research Scholar(2016-2017), PhD 2018-2022, Temple University


Students

Graduate Students

Brittany Bodnar, 2019-2023, Ph.D. in Biomedical Science program, Temple University Lewis Katz School of Medicine; Research Microbiologist (2024-)US Department of Agriculture (USDA) Agricultural Research Service (ARS)

Raj Putatunda, 2013-2018, Ph.D. in Biomedical Science program, Temple University Lewis Katz School of Medicine; Postdoc (2019-2021), University of Pensylvania; Scientist (2022-)at Astellas Gene Therapies

Sam Adhikari, Graduate Student (2011-2013)

Rotation Graduate Students

Rachel Pool (2009)

Jared S Czor (2010)

Anthony Iskander (2010)

Radhika K Adiga (2011)

Ellan Miller (2011)

Jeremy Hill (2012)

Adalto Alfredo Pontes Filho  (2013)

Philip Regis Fagan(2014)

Michael J Boyer ( 2015)

Lauren Cole (2016)

Mary Elizabeth Curtis (2017)

 

 

Undergraduate Students

Anam Butt (2009)

Samir Pate (2009)

Rujuta Shah (2010)

Danielle Bitner, Undergraduate (2011-2012)

Priya V. Soni, Undergraduate (2012-2013)

Nomble Lee, Undergraduate (2012)

Nathan Frankford (2013-2015)

 

 

 

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This site was last updated 05/01/2017